Research Fellow - Singapore - National University of Singapore

    National University of Singapore
    National University of Singapore Singapore

    22 hours ago

    $60,000 - $110,000 (SGD) per year *
    Description
    Job Title: Research Fellow (Life Sciences Institute, Neurobiology)

    Posting Start Date: 24/02/2026

    Job Description

    The Neurobiology Research Programme at the Life Sciences Institute, led by Professor Rickie Patani, invites applications for a highly motivated and accomplished Research Fellow to join a world-leading laboratory investigating the molecular mechanisms of motor neuron disease, with a particular focus on Amyotrophic Lateral Sclerosis (ALS).

    The Research Fellow will lead a strategically designed research programme examining the intersection between genomic instability and dysregulated RNA metabolism in ALS. A central objective will be to dissect how altered RNA processing — including intron retention — contributes to neurodegenerative vulnerability.

    Key Responsibilities
    • Conceive, design, and execute high-impact research initiatives aligned with programme strategy.
    • Establish, optimise, and oversee complex experimental platforms, ensuring rigorous methodological and analytical standards.
    • Lead and mentor junior researchers and students, fostering a collaborative and inclusive laboratory culture.
    • Integrate experimental and computational datasets, including high-throughput sequencing and advanced imaging analyses.
    • Prepare manuscripts for submission to leading peer-reviewed journals and contribute to competitive grant applications.
    • Present research findings at national and international scientific meetings.
    • Contribute to teaching activities within NUS, supporting curriculum development linked to translational neuroscience.
    • Maintain exemplary standards of data management, compliance, and laboratory governance.

    Qualifications

    Applicants should hold a PhD in Neuroscience, Biomedical Sciences, or a closely related discipline, with demonstrated expertise in ALS research or related neurodegenerative disorders.

    Essential Experience Includes
    • Human iPSC culture and differentiation into neural subtypes
    • Advanced molecular biology techniques
    • High-throughput data analysis (e.g., RNA sequencing, imaging datasets)
    • Experience with ALS-relevant mouse models

    Desirable Experience
    • Human post-mortem tissue analysis
    • Computational biology and bioinformatics (coding proficiency preferred)
    • Supervision of postgraduate or early-career researchers

    Candidates Must Demonstrate
    • A strong publication record in high-impact peer-reviewed journals
    • Evidence of scientific independence and international visibility
    • Excellent organisational, communication, and leadership skills
    • Commitment to mentoring and fostering an inclusive research environment
    * This salary range is an estimation made by beBee
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